Forensic DNA Research Group - International Burch University
 

Forensic DNA Research Group

About

Forensic DNA group deals with the techniques related to forensic DNA analysis and population genetic studies. The emphasis is on the analysis of STRs (short tandem repeats), which includes the use of several DNA extraction methods, PCR, electrophoresis and data analysis. STRs (Short tandem repeats) are the genetic markers which exist with different frequencies in different populations and population STR databases containing frequencies of STR loci are available to evaluate the DNA samples. They provide highly informative DNA data for the human identification purposes and comparative genetic studies among the populations. These STR markers have been in use for decent years in forensic genetics, parental testing, paternity testing, individual identification studies and comparative genetic analysis. These markers are very useful in forensic and population genetics studies. They had proved their efficiency in terms of the determination of relationships among related individuals and populations and they are especially valuable for the study of genetic relationships between closely related populations. However, STRs can be used to investigate genetic similarities between the sampled population and other populations that are not from the same biogeographical zone. Furthermore, a phylogenetic tree can be generated among different populations by using STR frequencies and they will provide an idea about historical human migrations associated with sample populations.

The other research projects that are planned to be realized throughout the activities of the group include, but are not limited to: mtDNA analysis, Y-STRs (examination of Y-linked markers in the male population), and the research related to the population genetics, since our University is an international environment and is very interesting for this type of research. The vision behind this group is to gather scientists interested in forensic DNA and to improve the experimental techniques related to forensic DNA in our university laboratories. Our main goal is the promotion of excellence in the research and the completion of the projects that will establish our laboratory as the friendly environment for research in forensic DNA analysis.

People
Prof. Dr. Damir Marjanović
Assis. Prof. Dr. Serkan Dogan, (contact person)
Mustafa Dogan, PhD candidate
Ramazan Tunc, PhD candidate
Hacer Konakli, PhD candidate
Senior Teaching Assistant Adna Ašić, PhD student
Senior Teaching Assistant Larisa Bešić, PhD student
Student Assistant Hasan Emin Balkaya, Master student
Publications

JOURNAL ARTICLES / CONFERENCES

Serkan Dogan, Adna Ašić, Gulsen Dogan, Larisa Bešić, Damir Marjanović; Turkish population currently residing in Sarajevo, Bosnia and Herzegovina – A synopsis of population genetics studies. In IUAES Intercongress, World Anthropologies and Privatization of Knowledge: Engaging Anthropology in Public, May 2016.
Doğan S, Doğan G, Ašić A, Bešić L, Klimenta B, Hukić M, Turan Y, Primorac D, Marjanović D; Prediction of the Y-Chromosome Haplogroups Within a Recently Settled Turkish Population in Sarajevo, Bosnia and Herzegovina, Collegium Antropologicum, Vol. 40, No. 1, pp. 1-7, Apr. 2016.
Babić, N., Dogan, S., Čakar, J., Pilav, A., Marjanović, D., & Hadžiavdić, V; Molecular diversity of 23 Y-chromosome short tandem repeat loci in the population of Tuzla Canton, Bosnia and Herzegovina,Annals of Human Biology, just accepted, 1-23, 2016.
Dogan, S., Babic, N., Gurkan, C., Goksu, A., Marjanovic, D., & Hadziavdic, V; Y-chromosomal haplogroup distribution in the Tuzla Canton of Bosnia and Herzegovina: A concordance study using four different in silico assignment algorithms based on Y-STR data,HOMO-Journal of Comparative Human Biology, 2016.
Marjanović, D., Hadžić Metjahi, N., Čakar, J., Džijan, S., Škaro, V., Projić, P., ..., Primorac, D.; Identification of human remains from the Second World War mass graves uncovered in Bosnia and Herzegovina,Croatian medical journal, Vol. 56, No. 3, pp. 257-262, 2015.
Gulsen Dogan, Serkan Dogan, Damir Marjanović; Prediction of the Y Chromosome Haplogroups within a Recently Settled Turkish Population in Sarajevo, Bosnia and Herzegovina. In 9th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Individualized Medicine, Jun. 2015.
Karmin, M, …, Damir Marjanovic, …; A recent bottleneck of Y chromosome diversity coincides with a global change in culture, Genome Research, Vol. 25, No. 4, pp. 459-466, Mar. 2015.
Serkan Dogan, Adna Ašić, Sanida Buljubašić, Larisa Bešić, Monia Avdić, Elma Ferić, ..., Damir Marjanović; Overview of European population clustering based on 23 Y-STR loci, Genetika, Vol. 47, No. 3, pp. 901-908, 2015.
Serkan Dogan, Adna Asic, Imer Muhovic, Larisa Besic, Damir Marjanovic; Overview of the Genetic STR Clustering among Worldwide Human Populations, International Journal of Human Genetics, Vol. 14, No. 3,4, Dec. 2014.
Serkan Dogan, Dragan Primorac, Damir Marjanovic; Genetic analysis of haplotype data for 23 Y-chromosome short tandem repeat loci in the Turkish population recently settled in Sarajevo, Bosnia and Herzegovina, Croatian Medical Journal, Vol. 55, No. 5, Oct. 2014.
Primorac D, Schanfield MS, Marjanović D; Basic Genetics and Human Genetic Variation. Book chapter - Forensic DNA Applications: An Interdisciplinary Perspective Book, CRC Press, USA, 2014.
Serkan Dogan, Lejla Kovacevic, Damir Marjanovic; Genetic Polymorphisms of 15 STR Loci within Turkish Student Population Living in Sarajevo, Bosnia and Herzegovina, Collegium Antropologicum, Vol. 37, No. 4, pp. 1313-1319, Dec. 2013.

PhD DISERTATIONS SUPERVISED / IN PROGRESS:

Serkan Dogan, completed in March 2015; "Analysis of Molecular Genetic Diversity within a Recently Settled Turkish Population in Sarajevo, Bosnia and Herzegovina"
Mustafa Dogan, in progress; “Analysis of Y chromosome STR haplotypes in the Northern Iraqi population"
Ramazan Tunc, in progress, “Analysis of molecular genetic diversity based on autosomal STR polymorphisms in the Northern Iraqi populations” Hacer Konakli, in progress, “Analysis of ACE and ACTN3 gene polymorphisms in Balkan populations”

MASTER THESIS SUPERVISED / IN PROGRESS:

Sanida Buljubašić, completed in June 2016; “Analysis of ACE gene polymorphisms in Gorani population”
Sanela Pelivani, completed in June 2016; “Analysis of ACTN3 gene polymorphisms in Gorani population”
Hasan Emin Balkaya, in progress, “Analysis of molecular genetic diversity in the Turkmen population of Northern Iraq”
Projects

COMPLETED PROJECTS


1. Project
Project Name:
Genetic Polymorphisms of 15 STR Loci within Turkish Student Population Living in Sarajevo, Bosnia and Herzegovina

Supported by: International Burch University
2. Project
Project Name:
Genetic analysis of haplotype data for 23 Y-chromosome short tandem repeat loci in the Turkish population recently settled in Sarajevo, Bosnia and Herzegovina

Supported by: International Burch University
3. Project
Project Name:
Overview of the Genetic STR Clustering among Worldwide Human Populations

Supported by: International Burch University
4. Project
Project Name:
Overview of the Y-STR Clustering among Worldwide Human Populations

Supported by: International Burch University
5. Project
Project Name:
Prediction of the Y-Chromosome Haplogroups within a Recently Settled Turkish Population in Sarajevo, Bosnia & Herzegovina

Supported by: International Burch University
6. Project
Project Name:
Analysis of ACE and ACTN3 gene polymorphisms in Gorani population

Supported by: International Burch University

ON GOING PROJECTS


1. Project
Project Name:
Analysis of ACE and ACTN3 gene polymorphisms in different Balkan populations

Supported by: International Burch University
2. Project
Project Name:
Analysis of molecular genetic diversity based on autosomal and Y-chromosomal STR polymorphisms in the Northern Iraqi populations

Supported by: International Burch University